Global Health and Pandemic: 18 publications

  1. Hoang SV, Nguyen KM, Le HTA, Tung AT, Huynh PVT, Le TV, Huynh KLA, Vuong N, Dhouibi N, Nguyen HT (2022) The effects of the COVID-19 lockdown on patients with chronic cardiovascular disease in Vietnam. J Infect Dev Ctries 16:268-275. doi: 10.3855/jidc.15002

  2. Raut A, Huy NT. Rising incidence of mucormycosis in patients with COVID-19: another challenge for India amidst the second wave? Lancet Respir Med. 2021 Jun 3:S2213-2600(21)00265-4.

  3. Sharma A, U V, Dong V, Raut A, Tawfik GM, Ng SJ, Ramly TAE, Nam NH, Pavlenko D, Alied M, Elnazir P, Marabea ME, Dumre SP, Elsayad A, Alqudah Q, Hegab MA, Zakaria SY, Nguyen APN, ElHawary AS, Huy NT. Universal checklist for COVID-19 control measures: consensus via a Delphi method. Clin Med (Lond). 2021 Mar;21(Suppl 2):25-26.

  4. Kansakar S, Dumre SP, Raut A, Huy NT†. From lockdown to vaccines: challenges and response in Nepal during the COVID-19 pandemic. Lancet Respir Med. 2021:S2213-2600(21)00208-3.

  5. Karimzadeh S, Bhopal R, Huy NT. Review of infective dose, routes of transmission, and outcome of COVID-19 caused by the SARS-COV-2: comparison with other respiratory viruses Epidemiol Infect. 2021. 149:e96.

  6. Fouda B, Tram HPB, Makram OM, Abdalla AS, Singh T, Hung IC, Raut A, Hemmeda L, Alahmar M, ElHawary AS, Awad DM, Huy NT†. Identifying SARS-CoV2 transmission cluster category: An analysis of country government database. J Infect Public Health. 2021;14(4):461-467.

  7. Igaki S, Duc NTM, Nam NH, Nga TTT, Bhandari P, Elhamamsy A, Lotify CI, Hewalla ME, Tawfik GM, Mathenge PG, Hashizume M, Huy NT*. Effectiveness of community and school-based sanitation interventions in improving latrine coverage: a systematic review and meta-analysis of randomized controlled interventions. Environ Health Prev Med. 26(1):26.

  8. Hsai NM, Matsui M, Ng CFS, Khaing CT, Imoto A, Sayed AM, Huy NT*, Kamiya Y, Moji K*. Satisfaction of Pregnant Women with Antenatal Care Services at Women and Children Hospital in South Okkalapa, Myanmar: A Facility-Based Cross-Sectional Study Triangulated with Qualitative Study. Patient Prefer Adherence. 2020;14:2489-2499.

  9. Latio LSY, Nam NH, Shah J, Smith C, Sakai K, Stonewall Shaban K, Idro R, Makoto N, Huy NT*, Hamano S, Moji K*. Economic burden of the persistent morbidity of nodding syndrome on caregivers in affected households in Northern Uganda. PLoS One. 2020;15(9):e0238643.

  10. Lessons Learned from the Re-emergent COVID-19 Cases in Areas of Long Reported No Community Transmission. Ibrahim Y, Raut A, Varney J, Sidhu A, Dong V, Huy NT†. Clin Infect Dis. 2020: doi: 10.1093/cid/ciaa1438

  11. Parrill A, Tsao T, Dong V, Huy NT†. SARS-CoV-2-induced immunodysregulation and the need for higher clinical suspicion for co-infection and secondary infection in COVID-19 patients. Journal of Microbiology, Immunology and Infection, doi: 10.1016/j.jmii.2020.08.016

  12. Pembi E, John S, Dumre SP, Ahmadu BU, Vuong NL, Ebied A, Mizukami S, Huy NT*, Cuevas LE, Hirayama K*. Impact of political conflict on tuberculosis notifications in North-east Nigeria, Adamawa State: a 7-year retrospective analysis. BMJ Open.

  13. Iglesias Rodríguez IM, Mizukami S, Manh DH, Thuan TM, Justiniano HA, Miura S, Ito G, Huy NT*, Smith C, Hirayama K*. Knowledge, behaviour and attitudes towards Chagas disease among the Bolivian migrant population living in Japan: a cross-sectional study. BMJ Open. 10(9):e032546.

  14. Smith C, van Velthoven MH, Truong ND, Nam NH, Anh VP, Al-Ahdal TMA, Hassan OG, Kouz B, Huy NT, Brewster M, Pakenham-Walsh N. How primary healthcare workers obtain information during consultations to aid safe prescribing in low-income and lower middle-income countries: a systematic review. BMJ Glob Health. 5(4):e002094

  15. Shah J, Karimzadeh S, Al-Ahdal TMA, Mousavi SH, Zahid SU, Huy NT. COVID-19: the current situation in Afghanistan. Lancet Glob Health.

  16. Ahmed AM, Mohammed AT, Vu TT, Khattab M, Doheim MF, Ashraf Mohamed A, Abdelhamed MM, Shamandy BE, Dawod MT, Alesaei WA, Kassem MA, Mattar OM, Smith C, Hirayama K, Huy NT†. Prevalence and burden of dengue infection in Europe: A systematic review and meta-analysis. Rev Med Virol. doi: 10.1002/rmv.2093.

  17. Ahmed AM, Giang HTN, Sherief G, Hosni S, Altibi AM, Huynh S, Tang NA, Cuong T, Tuan LQA, Vuong NL, Mohamed A, Ghorab, Muhammad, Ngan T, Sameh E, Elmaraezy A, Minh LHN, Hirayama K, Huy NT†. Introduction of novel surgical techniques: A survey on knowledge, attitude, and practice of surgeons. Surgical Innovation. 26(5):560-572.

  18. Morsy S, Dang TN, Kamel MG, Zayan AH, Makram OM, Elhady M, Hirayama K, Huy NT†. Prediction of Zika-confirmed cases in Brazil and Colombia using Google Trends. Epidemiol Infect. 30:1-3.

  19. Morra ME, Kien ND, Elmaraezy A, Abdelaziz OAM, Elsayed AL, Halhouli O, Montasr AM, Vu TL, Ho C, Foly AS, Phi AP, Abdullah WM, Mikhail M, Milne E*, Hirayama K, Huy NT*. Early vaccination protects against childhood leukemia: A systematic review and meta-analysis. Sci Rep. 7(1):15986

Research Methodological: 10 publications

  1. Tran L, Tam DNH, Elshafay A, Dang T, Hirayama K, Huy NT†. Quality assessment tools used in systematic reviews of in vitro studies: A systematic review. BMC Med Res Methodol. 2021;21(1):101.

  2. Sharma A, Minh Duc NT, Luu Lam Thang T, Nam NH, Ng SJ, Abbas KS, Huy NT†, Marušić A, Paul CL, Kwok J, Karbwang J, de Waure C, Drummond FJ, Kizawa Y, Taal E, Vermeulen J, Lee GHM, Gyedu A, To KG, Verra ML, Jacqz-Aigrain ÉM, Leclercq WKG, Salminen ST, Sherbourne CD, Mintzes B, Lozano S, Tran US, Matsui M, Karamouzian M. A Consensus-Based Checklist for Reporting of Survey Studies (CROSS). J Gen Intern Med. doi: 10.1007/s11606-021-06737-1.

  3. Tawfik GM, Giang HTN, Ghozy S, Altibi AM, Kandil H, Le HH, Eid PS, Radwan I, Makram OM, Hien TTT, Sherif M, Hossain AS, Thang TLL, Puljak L, Salem H, Numair T, Moji K, Huy NT†. Protocol registration issues of systematic review and meta-analysis studies: a survey of global researchers. BMC Med Res Methodol. 20(1):213.

  4. Tran L, Y MN, Thai Le Ba Nghia TLB, Hendam A, Vuong NL, Alzalal E, Ahmed M. Sayed AM, Hussain MM, Akash Sharma A, Tieu T, Peterson Gitonga Mathenge PG, Hirayama K, Alexander N*, Huy NT*. Frequent inappropriate use of unweighted summary statistics in systematic reviews of pathogen genotypes or genogroups. J Clin Epidemiol. 119:26-35. doi: 10.1016.

  5. Huy NT†, Elhadad H, Nam NH. Editorial overview of systematic reviews and meta-analyses on health in the tropics. Trop Med Health. 6;47:47

  6. Tawfik GM, Dila KAS, Mohamed MYF, Tam DNH, Kien ND, Ahmed AM, Huy NT†. A step by step guide for conducting a systematic review and meta-analysis with simulation data. Trop Med Health. 1;47:46.

  7. Giang HTN, Ahmed AM, Fala RY, Khattab MM, Othman MHA, Abdelrahman SAM, Thao LP, Gabl AEAE, Elrashedy SA, Lee PN, Hirayama K, Salem H, Huy NT†. Methodological steps used by authors of systematic reviews and meta-analyses of clinical trials: a cross-sectional study. BMC Med Res Methodol. 19(1):164.

  8. Elshafay A, Omran ES, Abdelkhalek M, El-Badry MO, Eisa HG, Fala SY, Dang T, Ghanem MAT, Elbadawy M, Elhady MT, Vuong NL, Hirayama K, Huy NT†. Reporting quality in systematic reviews of in vitro studies: a systematic review. Current Medical Research & Opinion. doi:10.1080/03007995.2019.1607270.

  9. Hai VN, Elawady SS, Mehyar GM, Abdelhamid AH, Mattar OM, Halhouli O, Vuong NV, Ali CDM, Hassan UH, Kien ND, Hirayama K, Huy NT†. Quality of Flow diagram in Systematic review and/or Meta-Analysis PLoS One 13(6):e0195955

  10. Turk T, Elhady MT, Rashed S, Abdelkhalek M, Nasef SA, Khallaf AM, Mohammed AT, Attia AW, Adhikari P, Amin MA, Hirayama K, Huy NT†. Quality of reporting web-based and non-web-based survey studies: what authors, reviewers and consumers should consider. PLoS One 13(6):e0194239

Clinical research: 43 publications

  1. Huong NTC, Karimzadeh S, Thanh NT, et alUpdated upper limit of normal for serum alanine aminotransferase value in Vietnamese populationBMJ Open Gastroenterology 2022;9:e000870. doi: 10.1136/bmjgast-2022-000870

  2. Thach TQ, Eisa HG, Hmeda AB, Faraj H, Thuan TM, Abdelrahman MM, Awadallah MG, Ha NX, Noeske M, Abdul Aziz JM, Nam NH, Nile ME, Dumre SP, Huy NT, Hirayama K. Predictive markers for the early prognosis of dengue severity: A systematic review and meta-analysis. PLoS Negl Trop Dis. 2021 Oct 5;15(10):e0009808. doi: 10.1371/journal.pntd.0009808. PMID: 34610027; PMCID: PMC8519480.

  3. Hung LT, Alshareef A, Al-Ahdal TMA, Anh PTT, Huan DQ, Do Van Trang, Zia S, Van Sy H, Huy NT. Predicting atrial fibrillation after cardiac surgery using a simplified risk index. J Electrocardiol. 2021 Apr 23;67:45-49

  4. Son PT, Reda A, Viet DC, Quynh NXT, Hung DT, Tung TH, Huy NT. Vox Sang. Exchange transfusion in the management of critical pertussis in young infants: a case series. 2021 May 18. doi: 10.1111/vox.13085.

  5. Nguyen TM, Huan VT,Reda A, Morsy S, Hoang ThiNam Giang HTN, Vo DucTri VD,Mau NK, Elfaituri MK, Truong HongHieu TH, Hung NT, Hirayama K, Huy NT†. Clinical features and outcomes of neonatal dengue at the Children’s Hospital 1, Ho Chi Minh, Vietnam. Journal of Clinical Virology Volume. 2021. 138,

  6. Tran L, Radwan I, Minh LHN, Low SK, Hashan MR, Gomaa MD, Abdelmongy M, Abdelaziz AI, Mohamed A, Tawfik GM, Mizukami S, Hirayama K, Huy NT†. Role of cytokines produced by T helper immune-modulators in dengue pathogenesis: A systematic review and meta-analysis. Acta Trop. 2021;216:105823.

  7. Mehta OP, Bhandari P, Raut A, Kacimi SEO, Huy NT† Coronavirus Disease (COVID-19): Comprehensive Review of Clinical Presentation. Front Public Health. 2021;8:582932.

  8. Manh DH, Weiss LN, Thuong NV, Mizukami S, Dumre SP, Luong QC, Thanh LC, Thang CM, Huu PT, Phuc LH, Nhung CTH, Mai NT, Truong NQ, Ngu VTT, Quoc DK, Ha TTN, Ton T, An TV, Halhouli O, Quynh LN, Kamel MG, Karbwang J, Huong VTQ, Huy NT, Hirayama K. Kinetics of CD4+ T Helper and CD8+ Effector T Cell Responses in Acute Dengue Patients. Front Immunol. 2020;11:1980

  9. Morsy S, Hashan MR, Hieu TH, Mohammed AT, Elawady SS, Ghosh P, Elgendy MA, Le HH, Hamad WMA, Iqtadar S, Dumre SP, Hirayama K, Huy NT†. The association between dengue viremia kinetics and dengue severity: A systemic review and meta-analysis. Rev Med Virol. e2121. doi: 10.1002/rmv.2121

  10. Pham TS, Reda A, Ngan Nguyen TT, Ng SJ, Huan VT, Viet DC, Huy NT†. Blood exchange transfusion in viral hepatitis in a small infant: a case report. Transfus Apher Sci. doi: 10.1016/j.transci.2020.102907.

  11. Karimzadeh S, Dong V, Hassan OG, Raut A, Fouda A, Parrill A, Eaton K, Huy NT†. Covid-19-induced coagulopathy and observed benefits with anticoagulation. Transfus Apher Sci. doi: 10.1016/j.transci.2020.102906

  12. Karimzadeh S, Manzuri A, Ebrahimi M*, Huy NT*. COVID-19 presenting as acute pancreatitis: Lessons from a patient in Iran. Pancreatology.

  13. Karimzadeh S, Raut A, Huy NT†. COVID-19 and pulmonary embolism: diagnostic imaging trends. J Nucl Med. doi: 10.2967/jnumed.120.248518.

  14. Mousavi SH, Shah J, Giang HTN, Al-Ahdal TMA, Zahid SU, Temory F, Paikan FM, Karimzadeh S, Huy NT. The first COVID-19 case in Afghanistan acquired from Iran. Lancet Infect Dis.

  15. Van Cuong L, Giang HTN, Linh LK, Shah J, Van Sy L, Hung TH, Reda A, Truong LN, Tien DX, Huy NT†. The first Vietnamese case of COVID-19 acquired from China. Lancet Infect Dis. 20(4):408-409.

  16. Sherif NA, Zayan AH, Elkady AH, Ghozy S, Ahmed AR, Omran ES, Taha EA, Eldesoky EA, Ebied A, Tieu T, Maraie N, Kamel MG, Ngo HT, Mattar OM, Hirayama K, Huy NT†. Mast cell mediators in relation to dengue severity: A systematic review and meta-analysis. Rev Med Virol. 30(1):e2084.

  17. Kien ND, El-Qushayri AE, Ahmed AM, Safi A, Mageed SA, Mehyar SM, Hashan MR, Karimzadeh S, Hirayama K, Huy NT†. Association of Allergic Symptoms with Dengue Infection and Severity: A Systematic Review and Meta-analysis. Virol Sin. 35(1):124

  18. Vásquez Velásquez C, Russomando G, Espínola EE, Sanchez Z, Mochizuki K, Roca Y, Revollo J, Guzman A, Quiroga B, Rios Morgan S, Vargas Ortiz R, Zambrana Ortega A, Espinoza E, Nishizawa JE, Kamel MG, Kikuchi M, Mizukami S, Na-Bangchang K, Huy NT, Hirayama K. IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia. PLoS Negl Trop Dis. 13(9):e0007715

  19. Vu-Ngoc H, Uyen NCMU, Thinh OP, Huy NT*, Duong PDT*. Analgesic effect of non-nutritive sucking in term neonates: a randomized controlled trial. Pediatrics and Neonatology. 61(1):106-113.

  20. Huy NT†, Karimzadeh S, Chico RM. Higher incidence of stroke in patients with dengue fever: Spurious association or causal link? Canadian Medical Association Journal. 191(24):E670

  21. Binh TQ*, Trang DV, Vuong NL, Khoi NV, Elfaituri MK, Loc TTH, KamelMG, Minh LHN, and Huy NT* NT-proBNP incorporated in prediction rule of major peri-operative adverse cardiac event in non-cardiac surgery. The Surgeon. 17(3):127-132.

  22. Phuong NTN, Manh DH, Dumre SP, Mizukami S, Weiss LN, Van Thuong N, Ha TTN, Phuc LH, Van An T, Tieu TM, Kamel MG, Morra ME, Huong VTQ, Huy NT*, Hirayama K*. Plasma cell-free DNA: a potential biomarker for early prediction of severe dengue. Ann Clin Microbiol Antimicrob. 13;18(1):10

  23. Giang HTN, Banno K, Minh LHN, Trinh LT, Loc LT, Eltobgy A, Tai LLT, Khan A, Tuan NH, Reda Y, Samsom M, Nam NT, Huy NT†, Hirayama K. Dengue hemophagocytic syndrome: A systematic review and meta-analysis on epidemiology, clinical signs, outcomes, and risk factors. Rev Med Virol. 8(6):e2005.

  24. Inokuchi M, Dumre SP, Mizukami S, Tun MMN, Kamel MG, Manh DH, Phuc LH, Van Thuong N, Van An T, Weiss LN, Turk T, Dang TN, Huong VTQ, Morita K, Huy NT*, Hirayama K*. Association between dengue severity and plasma levels of dengue-specific IgE and chymase. Arch Virol. 163(9):2337-2347.

  25. Manh DH, Mizukami S, Dumre SP, Raekiansyah M, Senju S, Nishimura Y, Krbwang J, Huy NT, Morita K, Hirayama K. iPS cell serves as a source of dendritic cells for in vitro dengue virus infection model. Journal of General Virology. 99(9):1239-124.

  26. Morra ME, Altibi AM, Iqtadar S, Minh LHN, Elawady SS, Hallab A, Elshafay A, Omer OA, Iraqi A, Adhikari P, Labib JH, Elhusseiny KM, Elgebaly A, Yacoub S, Huong LTM, Hirayama K, Huy NT†. Definitions for Warning Signs and Signs of Severe Dengue According to The WHO 2009 Classification: Systematic Review of Literature. Reviews in Medical Virology 28(4):e1979.

  27. Morra ME, Thanh LV, Kamel MG, Ghazy AA, Altibi AM, Dat LM, Thy TNX, Vuong NL, Mostafa MR, Ahmed Sara Ibrahim, ElabdSS, Fathima S, Vu TLH, Omrani AS, Memish ZA, Hirayama K, Huy NT†. Clinical outcomes of current medical approaches for Middle East Respiratory Syndrome: A systematic Review and Meta-analysis. Reviews in Medical Virology 28(3):e1977.

  28. Morra ME, Elshafay A, Kansakar AR, Mehyar GM, Dang NPH, Mattar OM, Iqtadar S, Mostafa MR, Hai VN, Vu TL, Ghazy AA, Kaboub F, Huy NT†, Hirayama K. Definition of "persistent vomiting" in current medical literature: A systematic review. Medicine (Baltimore). 96(45):e8025

  29. Ohyama K#, Huy NT#, Yoshimi H#, Kishikawa N, Nishizawa JE, Roca Y, Revollo Guzmán RJ, Velarde FU, Kuroda N, Hirayama K. Proteomic profile of circulating immune complexes in chronic Chagas disease. Parasite Immunol. 38(10):609-17

  30. Vuong NL, Manh DH, Mai NT, Phuc le H, Luong VT, Quan VD, Thuong NV, Lan NT, Nhon CT, Mizukami S, Doan NN, Huong VT, Huy NT†, Hirayama K. Criteria of "persistent vomiting" in the WHO 2009 warning signs for dengue case classification. Trop Med Health. 16;44:14.

  31. Nhi DM, Huy NT*, Ohyama K, Kimura D, Lan NT, Uchida L, Thuong NV, Nhon CT, Phuc le H, Mai NT, Mizukami S, Bao LQ, Doan NN, Binh NV, Quang LC, Karbwang J, Yui K, Morita K, Huong VT, Hirayama K*. (2016, Feb) A Proteomic Approach Identifies Candidate Early Biomarkers to Predict Severe Dengue in Children. PLoS Negl Trop Dis. 10(2):e0004435

  32. Vasquez Velasquez C, Roman AD, Lan NT, Huy NT, Mercado ES, Espino FE, Perez ML, Huong VT, Thuy TT, Tham VD, Nga CT, Ha TT, Bilar JM, Bajaro JD, Baello BQ, Kikuchi M, Yasunami M, Morita K, Watanabe N, Karbwang J, Hirayama K. Alpha tryptase allele of Tryptase 1 (TPSAB1) gene associated with Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in Vietnam and Philippines. Hum Immunol. 76(5):318-23

  33. Mercado ES, Espino FE, Perez ML, Bilar JM, Bajaro JD, Huy NT, Baello BQ, Kikuchi M, Hirayama K. HLA-A*33:01 as protective allele for severe dengue in a population of Filipino children. PLoS One. 10(2):e0115619

  34. Mangione JNA, Huy NT, Lan NTP, Mbanefo EC, Ha TTN, Bao LQ, Nga CTP, Tuong VV, Dat TV, Thuy TT, Tuan HM, Huong VTQ, Hirayama K. The Association of Cytokines with Severe Dengue in Children.Tropical Medicine and Health. 42(4):137-44

  35. Huong VTL, Ha N, Huy NT#, Horby P, Nghia HDT, Thiem VD, Zhu X, Hoa NT, Hien TT, Zamora J, Schultsz C, Wertheim H, and Hirayama K. Epidemiology, clinical manifestations, and outcomes of Streptococcus suis infection in humans. Emerging infectious diseases. 20(7):1105-14

  36. Huy NT, Thao NTH, Ha TTN, Lan NTP, Nga PTT, Thuy TT, Tuan HM, Nga CTP, Tuong VV, Dat TV, Huong VTQ, Karbwang J, and Hirayama K. Development of clinical decision rules to predict recurrent shock. Crit Care.17(6):R280, 2013

  37. Huy NT, Van Giang T, Thuy DH, Kikuchi M, Hien TT, Zamora J, Hirayama K. Factors Associated with Dengue Shock Syndrome: A Systematic Review and Meta-analysis. PLoS Negl Trop Dis. 7(9):e2412

  38. Huy NT, Trieu HT, Okamoto K, Ninh TTH, Ha TTN, Morita K, Huong VTQ, Lan NTP, Thuy TT, Nga CTP, Kikuchi M, Kuroda N, Karbwang J, Ohyama K, Hirayama K. Proteomic Profile of Circulating Immune Complexes in Dengue Infected Patients. J Trop Dis. 1(2) 109

  39. Huy NT, Thao NTH, Tuan NA, Khiem NT, Moore CC, Diep DTN, and Hirayama K. Performance of Thirteen Clinical Rules to Distinguish Bacterial and Presumed Viral Meningitis in Vietnamese Children. PLoS ONE 7(11): e50341.

  40. Huy NT*, Hang LTT, Boamah D, Lan NT, Thanh PV, Watanabe K, Huong VT, Kikuchi M, Ariyoshi K, Morita K, Hirayama K*. Development of a Single Tube Loop-mediated Isothermal Amplification Assay for Detection of Four Pathogens of Bacterial Meningitis. FEMS Microbiol Lett. 337(1):25-30, 2012

  41. Furuta T, Murao LA, Lan NT, Huy NT, Huong VT, Thuy TT, Tham VD, Nga CT, Ha TT, Ohmoto Y, Kikuchi M, Morita K, Yasunami M, Hirayama K, *Watanabe N. Association of mast cell-derived VEGF and proteases in dengue shock syndrome. PLoS Negl Trop Dis. 6(2), 2012

  42. Ha TTN, Huy NT, Murao LA, Lan NTP, Thuy TT, Tuan HM, Nga CTP, Tuong VV, Dat TV, Kikuchi M, Yasunami M, Morita K, Huong VTQ, and Hirayama K. Elevated Levels of Cell-free Circulating DNA in Patients with Acute Dengue Virus Infection. PLoS One. 6(10) e25969

  43. Huy NT, Thao NTH, Diep DTN, Kikuchi M, Zamora J, and Hirayama K. Cerebrospinal fluid lactate concentration to distinguish bacterial from aseptic meningitis: a systemic review and meta-analysis. Crit Care Dec 31, 14(6):R240.

  44. Hoa PT, Huy NT, Thu LT, Nga CN, Nakao K, Eguchi K, Chi NH, Hoang BH, Hirayama K. A Randomized-Controlled Study investigating Viral Suppression and Serological Response following PreS1/PreS2/S Vaccine Therapy Combined with Lamivudine in HBeAg-positive Chronic Hepatitis B Patients. Antimicrob Agents Chemother. 53. 5134-40, 2009

Ethics and Educations: 3 publications

  1. Trung LQ, Morra ME, Truong ND, Turk T, Elshafie A, Foly A, Hien Tam DN, Iraqi A, Hong Van TT, Elgebaly A, Ngoc TN, Le Huy Vu T, Chu NT, Hirayama K, Karbwang J, Huy NT†. A systematic review finds underreporting of Ethics Approval, Informed Consent, and Incentives in Clinical Trials. J Clin Epidemiol. 91:80-86

  2. Sgro A, Kamel MG, Vuong TH, Ahmed AM, Huy NT†. Online Research Club: A mentoring program for undergraduate students. Med Teach. 39(9):1003

  3. Tam NT, Huy NT†, Thoa LTB, Long NP, Trang NTH, Hirayama K, and Karbwang J. (2015, Mar); Three decades of participants’ understanding of informed consent in clinical trials: a systematic review and meta-analysis. Bulletin of the World Health Organization. 93(3):186-198H

Drug discovery and basic science: 43 publications

  1. Tam DNH, Tawfik GM, El-Qushayri AE, Mehyar GM, Istanbuly S, Karimzadeh S, Tu VL, Tiwari R, Van Dat T, Nguyen PTV*, Hirayama K, Huy NT*. Correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds. Malar J. 19(1):298.

  2. Eklemichael AA, Mizukami S, Toume K, Mosaddeque F, Kamel MG, Kaneko O, Komatsu K, Karbwang J, Huy NT, Hirayama K. Anti-malarial Activity of Traditional Kampo Medicine Coptis Rhizome Extract and Its Major Active Compounds. Malar J. 19(1):204

  3. Mosaddeque F, Mizukami S, Kamel MG, Teklemichae AA, Dat TV, Mizuta S, Toan DV, Ahmed AM, Vuong NL, Elhady MT, Giang HTN, Dang TN, Fukuda M, Huynh LK, Tanaka Y, Egan TJ, Kaneko O, Huy NT*, Hirayama H*. Prediction model for anti-malarial activities of hemozoin inhibitors using physicochemical properties. Antimicrob Agents Chemother. 62(5). e02424-17.

  4. Helegbe GK, Huy NT, Yanagi T, Shuaibu MN, Kikuchi M, Cherif MS, Hirayama K. Elevated IL-17 levels in semi-immune anaemic mice infected with Plasmodium berghei ANKA. Malar J. 17(1):169.

  5. Lemma MT, Ahmed AM, Elhady MT, Ngo HT, Vu TLH, Campos-Alberto1 E, Sang TK, Sayed A, Mizukami S, Na-Bangchang K, Huy NT*, Hirayama K, Karbwang J*. Medicinal plants for in vitro antiplasmodial activities: A systematic review of literature. Parasitol Int. 66(6) 713-720.

  6. Lam BQ, Dang NM, Huy NT, Hamano S, Hirayama K. Tacrolimus Prevents Murine Cerebral Malaria. Immunology. 150(2):155-161.

  7. Huy NT*, Chi PL, Nagai J, Dang TN, Mbanefo EC, Ahmed AM, Long NP, Thoa LT, Hung LP, Afaf T, Kamei K, Ueda H, Hirayama K*. High-throughput screening and prediction models building for novel hemozoin inhibitors using physicochemical properties. Antimicrob Agents Chemother. 61(2): e01607-16.

  8. Cherif MS, Mbanefo EC, Shuaibu MN,Kodama Y, Avenido EF , Campos-Alberto E, Mizukami S, Camara F, Helegbe GK, Kikuchi M, Yanagi T, Sasaki H, Huy NT, Karbwang J, and Hirayama K. Human-applicable dendrigraft poly-L-lysine-based nanoparticle-coated Plasmodium yoelii-transamidase DNA vaccine is immunogenic and protective as the polyethylenimine-based formulation. Journal of Bioactive and Compatible Polymers. 31.4:334-347

  9. Men TT, Thanh DN, Yamaguchi M, Suzuki T, Hattori G, Arii M, Huy NT, Kamei K. A Drosophila Model for Screening Antiobesity Agents. Biomed Res Int. 2016:6293163.

  10. Men TT, Binh TD, Yamaguchi M, Huy NT, Kamei K. Function of Lipid Storage Droplet 1 (Lsd1) in Wing Development of Drosophila melanogaster. Int J Mol Sci. 29;17(5)

  11. Mbanefo EC, Kumagai T, Kodama Y, Kurosaki T, Furushima-Shimogawara R, Cherif MS, Mizukami S, Kikuchi M, Huy NT, Ohta N, Sasaki H, Hirayama K. Immunogenicity and anti-fecundity effect of nanoparticle coated glutathione S-transferase (SjGST) DNA vaccine against murine Schistosoma japonicum infection. Parasitol Int. 64(4):24-31

  12. Mbanefo EC, Kumagai T, Kodama Y, Kurosaki T, Furushima-Shimogawara R, Cherif MS, Mizukami S, Kikuchi M, Huy NT, Ohta N, Sasaki H, Hirayama K. Immunogenicity and anti-fecundity effect of nanoparticle coated glutathione S-transferase (SjGST) DNA vaccine against murine Schistosoma japonicum infection. Parasitol Int. 64(4):24-31

  13. Bao LQ, Nhi DM, Huy NT, Kikuchi M, Yanagi T, Hamano S, Hirayama K. Splenic CD11c(+) cells derived from semi-immune mice protect naïve mice against experimental cerebral malaria. Malar J. 14(1):23

  14. Cherif MS, Shuaibu MN, Kodama Y, Helegbe GK, Kikuchi M, Ichinose A, Yanagi T, Sasaki H, Yui K, Tien NH, Karbwang J, Hirayama K. Nanoparticle formulation enhanced protective immunity provoked by PYGPI8p-transamidase related protein (PyTAM) DNA vaccine in Plasmodium yoelii malaria model. Vaccine.32(17):1998-2006

  15. Mbanefo EC, Kikuchi M, Huy NT, Shuaibu MN, Cherif MS, Yu C, Wakao M, Suda Y, Hirayama K. Characterization of a Gene Family Encoding SEA (Sea-urchin Sperm Protein, Enterokinase and Agrin)-Domain Proteins with Lectin-Like an Heme-Binding Properties from Schistosoma japonicum. PLoS Negl Trop Dis.8(1):e2644

  16. Helegbe GK, Huy NT, Yanagi T, Shuaibu MN, Kikuchi M, Cherif MS, Hirayama K. Anti-erythropoietin antibody levels and its association with anaemia in different strains of semi-immune mice infected with Plasmodium berghei ANKA. Malar J. 12 (1), 1-10

  17. Huy NT, Shima Y, Maeda A, Men TT, Hirayama K, Hirase A, Miyazawa A, and Kamei K. Phospholipid Membrane-Mediated Hemozoin Formation: The Effects of Physical Properties and Evidence of Membrane Surrounding Hemozoin. PLoS One. 8(7):e70025

  18. Bao LQ, Huy NT*, Kikuchi M, Yanagi T, Senba M, Shuaibu MN, Honma K, Yui K, Hirayama K. CD19(+) B Cells Confer Protection against Experimental Cerebral Malaria in Semi-Immune Rodent Model. PLoS One. 8(5):e64836

  19. Helegbe GK, Huy NT, Yanagi T, Shuaibu MN, Kikuchi M, Cherif MS, Hirayama K. Anti-erythropoietin antibody levels and its association with anaemia in different strains of semi-immune mice infected with Plasmodium berghei ANKA. Malar J. 12 (1), 1-10

  20. Huy NT, Shima Y, Maeda A, Men TT, Hirayama K, Hirase A, Miyazawa A, and Kamei K. Phospholipid Membrane-Mediated Hemozoin Formation: The Effects of Physical Properties and Evidence of Membrane Surrounding Hemozoin. PLoS One. 8(7):e70025

  21. Bao LQ, Huy NT*, Kikuchi M, Yanagi T, Senba M, Shuaibu MN, Honma K, Yui K, Hirayama K. CD19(+) B Cells Confer Protection against Experimental Cerebral Malaria in Semi-Immune Rodent Model. PLoS One. 8(5):e64836

  22. Boamah D, Kikuchi M, Huy NT, Okamoto K, Chen H, Ayi I, Boakye DA, Bosompem KM, Hirayama K. Immunoproteomics identification of major IgE and IgG4 reactive Schistosoma japonicum adult worm antigens using chronically infected human plasma. Tropical Medicine and Health. 40 (3), 89-102.

  23. Men TT, Huy NT*, Trang DT, Shuaibu MN, Hirayama K, Kamei K. A simple and inexpensive haemozoin-based colorimetric method to evaluate anti-malarial drug activity. Malar J. 11(1):272

  24. Nhien NT, Huy NT, Uyen DT, Deharo E, Hoa PT,, Harada S, Hirayama K, and Kamei K. Effect of inducers, incubation time and heme concentration on IC50 value variation in anti-heme crystallization assay. Tropical Medicine and Health. 39 (4),119-126

  25. Helegbe GK, Yanagi T, Senba M, Huy NT, Shuaibu MN, Yamazaki A, Kikuchi M, Yasunami M, and Hirayama K. Histopathological studies in two strains of semi-immune mice infected with Plasmodium berghei ANKA after chronic exposure. Parasitol. Res. 2011 108(4):807-14.

  26. Helegbe GK, Huy NT, Yanagi T, Shuaibu MN, Kikuchi M, Yasunami M, and Hirayama K. Microfluorometric assay for quantification of anti-erythrocytic antibody level in sera of Plasmodium berghei ANKA infected semi-immune mice. Tropical Medicine and Health. 38. 4: 127-131

  27. Nhien NT, Huy NT, Naito M, Oida T, Uyen DT, Huang M, Kikuchi M, Harada S, Nakayama K, Hirayama K, Kamei K. Neutralization of Toxic Heme by Porphyromonas gingivalis Hemoglobin Receptor. J Biochem. 147(3):317-25

  28. Helegbe GK, Huy NT, Yanagi T, Shuaibu MN, Yamazaki A, Kikuchi M, Yasunami M, Hirayama K. Rate of red blood cell destruction varies in different strains of mice infected with Plasmodium berghei-ANKA after chronic exposure. Malar J. 5. 91

  29. Uyen DT, Huy NT, Trang DT, Nhien NT, Oida T, Hirayama K, Harada S, Kamei K. Effects of amino acids on malarial heme crystallization. Biol Pharm Bull. 31, 1483-1488

  30. Huy NT, Mizunuma K, Kaur K, Thuy Nhien NT, Jain M, Uyen DT, Harada S, Jain R, and Kamei K. 2-tert-butyl-8-quinolinamines Exhibits Potent Blood-schizontocidal Antimalarial Activity via Inhibition of the Heme Crystallization. Antimicrob Agents Chemother. 51, 2842-2847

  31. Huy NT, Maeda A, Uyen DT, Trang DT, Sasai M, Shiono T, Oida T, Harada S, and Kamei K. Alcohols Induce Beta-hematin Formation via the Dissociation of Aggregated Heme and Reduction in Interfacial Tension of the Solution. Acta Trop. 101, 130-138

  32. Huy NT, Uyen DT, Maeda A, Trang DT, Oida T, Harada S, and Kamei K. A simple colorimetric inhibition assay of heme crystallization for the high throughput screening of antimalarial compounds. Antimicrob Agents Chemother. 51, 350-353

  33. Huy NT, Uyen DT, Sasai S, Trang DTX, Shiono T, Harada S, and Kamei K. A simple and rapid colorimetric method to measure hemozoin crystal growth in vitro. Anal Biochem. 354, 305-307

  34. Huy NT, Trang DTX, Kariu T, Sasai S, Saida K, Harada S, and Kaeko Kamei. Leukocyte Activation by Malarial Pigment. Parasitol Int. 55, 75-81

  35. Trang DTX, Huy NT, Uyen DT, Sasai S, Shiono T, Harada S, and Kamei K. Inhibition assay of beta-hematin formation initiated by lecithin for screening new antimalarial drugs. Anal Biochem. 349, 292-296

  36. Huy NT, Trang DTX, Uyen DT, Sasai S, Harada S, and Kamei K. An improved colorimetric method for quantitation of heme using tetramethylbenzidine as substrate. Anal Biochem. 344, 289-291

  37. Trang DTX, Huy NT, Kariu T, Tajima K, and Kamei K. One-step concentration of malarial parasite-infected red blood cells and removal of contaminating white blood cells. Malar J. 3, 1-7

  38. Huy NT, Takano R, Hara S, Kamei K. Enhancement of heme-induced membrane damage by the anti-malarial clotrimazole: the role of colloid-osmotic forces. Biol Pharm Bull. 27, 361-365

  39. Huy NT, Serada S, Trang DTX, Takano R, Kondo Y, Kanaori K, Tajima K, Hara S, and Kamei K. Neutralization of toxic heme by Plasmodium falciparum histidine-rich protein 2. J. Biochem 133, 693-698

  40. Huy NT, Kamei K, Kondo Y, Serada S, Kanaori, Takano R, Tajima K, and Hara S. Effect of antifungal azoles on the heme detoxification system of malarial parasite. J. Biochem. 131, 437-444

  41. Huy NT, Kamei K, Yamamoto T, Kondo Y, Kanaori K, Takano R, Tajima K, and Hara S. Clotrimazole binds to heme and enhances heme-dependent hemolysis: Proposed antimalarial mechanism of clotrimazole. J. Biol. Chem. 277, 4152-4158

  42. Kamei K, Wu X, Minami K, Xu X, Huy NT, Takano R, Kato H, and Hara S. The analysis of heparin-protein interactions using evanescent wave biosensor with regioselectively desulfated heparins as the ligands. Anal. Biochem. 295, 203-213

  43. Takano R, Nagai T, Wu X, Xu X, Huy NT, Kamei K, and Saburo Hara. Sulfation of polysacchrides using monomethyl sulfate. J. Carbohydrate Chemistry 19, 1185-1190

Other fields and systematic review for teaching students: 60 publications

  1. Vuong NL, Elfaituri MK, Eldoadoa M, Karimzadeh S, Mokhtar MA, Eid PS, Nam NH, Mostafa MR, Radwan I, Zaki MMM, Al Khudari R, Kassem M, Huy NT. Saphenous vein harvesting techniques for coronary artery bypass grafting: a systematic review and meta-analysis. Coron Artery Dis. 2021 May 18. doi: 10.1097/MCA.0000000000001048.

  2. Tiwariab R, Tam DNH JafferShah J, Moriyama M, Varney J, Huy NT†. Effects of sleep intervention on glucose control: A narrative review ofclinical evidence. Primary Care Diabetes. 2021. S1751-9918(21)00047-4.

  3. Elfaituri MK, Ghozy S, Ebied A, Morra ME, Hassan OG, Alhusseiny A, Abbas AS, Sherif NA, Fernandes JL, Huy NT†. Amlodipine as adjuvant therapy to current chelating agents for reducing iron overload in thalassaemia major: a systematic review, meta-analysis and simulation of future studies. Vox Sang. 2021. doi: 10.1111/vox.13083.

  4. El-Ozairy HSE, Mady OM, Tawfik GM, Elhennawy AM, Teaima AA, Ebied A, Huy NT†. Outcomes of combined use of topical and intravenous tranexamic acid on surgical field quality during functional endoscopic sinus surgery: A randomized controlled trial. Head Neck. 2021; doi: 10.1002/hed.26610.

  5. Varney J, Rivera A, Dong V, Tieu P, Zia S, Huy NT†. Mini-review on the properties and possible applications of therapeutic oxygen carrier Hemarina-M101. Transfus Apher Sci. 2020:103016.

  6. Mannan SB, Elhadad H, Loc TTH, Sadik M, Mohamed MYF, Nam NH, Thuong ND, Hoang-Trong BL, Duc NTM, Hoang AN, Elhusseiny KM, Minh LHN, Quynh TTH, Nghia TLB, Mai Nhu Y, Tieu TM, Hirayama K, Huy NT*, Hamano S*. Prevalence and associated factors of asymptomatic leishmaniasis: A systematic review and meta-analysis. Parasitol Int. 102229.

  7. Tawfik GM, Dibas M, Dung NM, Alkhebairy AA, Mahmoud MH, Ibrahim MH, Abd Elhady NR, Sayed AM, Gehad AS, Abdelrahman AS, Elfaituri MK, Nam NH, El-Qushayri AE, Huy NT†. Concordance of bone and non-bone specimens in microbiological diagnosis of osteomyelitis: A systematic review and meta-analysis. J Infect Public Health. 2020;13(11):1682-1693

  8. Hashan MR, Elhusseiny KM, Huu-Hoai L, Tieu TM, Low SK, Minh LHN, Nghia TLB, Loc LQ, Y MN, Eid PS, Abed M, Elkolaly SS, Tawfik GM, Huy NT†. Effect of nitazoxanide on diarrhea: A systematic review and network meta-analysis of randomized controlled trials. Acta Trop. doi: 10.1016/j.actatropica.2020.105603.

  9. Kamel MG, El-Qushayri AE, Sayed AK, Huy NT†. Using the primary site as a prognostic tool for nodal mantle cell lymphoma: a SEER-based study.

  10. J Comp Eff Res. doi: 10.2217/cer-2020-0083

  11. Eid PS, Ibrahim DA, Zayan AH, Elrahman MMA, Shehata MAA, Kandil H, Abouibrahim MA, Duy LM, Shinkar A, Elfaituri MK, Minh LHN, Fahmy MM, Tam DNH, Vuong NL, Shah J, Do VBD, Hirayama K, Huy NT†. Comparative effects of furosemide and other diuretics in the treatment of heart failure: a systematic review and combined meta-analysis of randomized controlled trials. Heart Fail Rev. doi: 10.1007/s10741-020-10003-7.

  12. Ghozy S, Dung NM, Morra ME, Morsy S, Elsayed GG, Tran L, Minh LHN, Abbas AS, Loc TTH, Hieu TH, Dung TC, Huy NT†. Efficacy of kinesio taping in treatment of shoulder pain and disability: a systematic review and meta-analysis of randomised controlled trials. Physiotherapy107:176-188.

  13. Tam DNH, Nam NH, Elhady MT, Tran L, Hassan OG, Sadik M, Tien PTM, Elshafei GA, Huy NT†. Effects of Mulberry on the Central Nervous System: A Literature Review. Curr Neuropharmacol. doi: 10.2174/1570159X18666200507081531

  14. Sayed AM, Morsy S, Tawfik GM, Naveed S, Minh-Duc NT, Hieu TH, Ali ZA, Shinkar A, Doheim MF, Hashan MR, Huy NT†. The best route of administration of lavender for anxiety: a systematic review and network meta-analysis.

  15. Gen Hosp Psychiatry;64:33-40.

  16. Kamel MG, Istanbuly S, Abd-Elhay FA, Mohamed MYF, Huu-Hoai L, Sadik M, Dibas M, Huy NT†. Examined and Positive Lymph Node Counts Are Associated with Mortality in Prostate Cancer: A Population-Based Analysis. Urol Int. 8:1-11.

  17. Ebied A, Yousif M, Nam NH, Elhamamsy AR, Hassan OG, Mostafa EM, Nguyen GJ, Hirayama K, Huy NT†. Primary lymph node sites in Hodgkin lymphoma and the risk of second primary cancers: a population-based study. Future Oncol. 16(9):451-467.

  18. Ghozy S, Tran L, Naveed S, Quynh TTH, Helmy Zayan A, Waqas A, Sayed AKH, Karimzadeh S, Hirayama K, Huy NT†. Association of breastfeeding status with risk of autism spectrum disorder: A systematic review, dose-response analysis and meta-analysis. Asian J Psychiatr. 48:101916

  19. El-Qushayri AE, Kamel AMA, Faraj HA, Vuong NL, Diab OM, Istanbuly S, Elshafei TA, Makram OM, Sattar Z, Istanbuly O, Mukit SAA, Elfaituri MK, Low SK, Huy NT†. Association between pet ownership and cardiovascular risks and mortality: a systematic review and meta-analysis. J Cardiovasc Med (Hagerstown). doi: 10.2459/JCM.0000000000000920.

  20. Ghozy S, Nam NH, Radwan I, Karimzadeh S, Tieu TM, Hashan MR, Abbas AS, Eid PS, Vuong NL, Khang NV, Elgabalawy E, Sayed AK, Hoa PTL, Huy NT†. Therapeutic efficacy of hepatitis B virus vaccine in treatment of chronic HBV infections: A systematic review and meta-analysis. Rev Med Virol. e2089. doi: 10.1002/rmv.2089.

  21. Shafik AG*, Alkady HA, Tawfik GM, Mohamed AM, Rabie TM, Huy NT*. Computed tomography evaluation of internal nasal valve angle and area and its correlation with NOSE scale for symptomatic improvement in rhinoplasty. Braz J Otorhinolaryngol. pii: S1808-8694(19)30115-6.

  22. Tam DNH, Mostafa EM, Tu VL, Rashidy AI, Matenoglou E, Kassem M, Soa DT, Bayumi A, Emam HES, Tran L, Dat TV, Huy NT†. Efficacy of chalcone and xanthine derivatives on lipase inhibition: A systematic review. Chem Biol Drug Des. doi: 10.1111/cbdd.13626

  23. Sherif NA, Morra ME, Thanh LV, Elsayed GG, Elkady AH, Elshafay A, Kien ND, Al-Habbaa A, Minh LHN, Y MN, Nghia TLB, Mohammed AT, Eid PS, Turk T, Hirayama K, Huy NT†. Torasemide versus furosemide in treatment of heart failure: A systematic review and meta-analysis of randomized controlled trials. J Eval Clin Pract. 26(3):842-851.

  24. Morsy S, Khalil SM, Doheim MF, Kamel MG, El-Basiony DSM, Hassan HIA, Eisa AA, Ngoc CTA, Dang NP, Hirayama K, Huy NT†. Efficacy of ethyl-EPA as a treatment for Huntington disease: A systematic review and meta-analysis. Acta Neuropsychiatr. 31(4):175-185.

  25. Low SK, Giannis D, Bahaie NS, Trong BLH, Moris D, Huy NT†. Competing Mortality in Patients With Neuroendocrine Tumors. Am J Clin Oncol. 42(8):668-674

  26. Elhusseiny KM, Abd-Elhay FA, Kamel MG, Abd El Hamid Hassan HH, El Tanany HHM, Hieu TH, Tieu TM, Low SK, Hou V, Dibas M, Huy NT†. Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer. Head Neck. 41(8):2625-2635

  27. Low SK, Zayan AH, Istanbuly O, Minh Duc NT, Ebied A, Mohamed Tawfik G, Huy NT†. Prognostic factors and nomogram for survival prediction in patients with primary pulmonary lymphoma: a SEER population-based study. Leuk Lymphoma. 19:1-11

  28. Abbas AS, Ghozy S, Minh LHN, Hashan MR, Soliman AL, Van NT, Hirayama K, Huy NT†. Honey in Bronchial Asthma: From Folk Tales to Scientific Facts. J Med Food. 22(6):543-550.

  29. Hieu TH, Dibas M, Surya Dila KA, Sherif NA, Hashmi MU, Mahmoud M, Trang NTT, Abdullah L, Nghia TLB, Y MN, Hirayama K, Huy NT†. Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep quality: A systematic review and meta-analysis of randomized trials and quasi-randomized trials. Phytother Res. 33(6):1604-1615.

  30. Tawfik GM, Hashan MR, Abdelaal A, Tieu TM, Huy NT*. A commentary on the medicinal use of marijuana.Trop Med Health. 24;47:35

  31. Mathenge PG, Low SK, Vuong NL, Mohamed MYF, Faraj H, Alieldin G, Al Khudari R, Yahia NA, Khan A, Diab OM, Mohamed YM, Zayan AH, Tawfik GM, Huy NT*, Hirayama K*. Efficacy and resistance of different artemisinin-based combination therapies: a systematic review and network meta-analysis. Parasitol Int. doi: 10.1016/j.parint.2019.04.016.

  32. Elshafay A, Hieu TH, Doheim MF, Kassem MAM, ELdoadoa MF, Holloway SK, Abo-Elghar H, Hirayama K, Huy NT†. Efficacy and Safety of Valproic Acid for Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis. CNS Drugs. 33(3):239-250.

  33. Abdellatif M, Ghozy S, Kamel MG, Elawady SS, Ghorab MME, Attia AW, Le Huyen TT, Duy DTV, Hirayama K, Huy NT†. Association between exposure to macrolides and the development of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. Eur J Pediatr. 178(3):301-314

  34. Radwan I, Magdy Khattab M, Mahmoud AR, Nghia TLB, Y MN, Trung DT, Hirayama K, Huy NT†. Systematic review of spontaneous splenic rupture in dengue-infected patients. Rev Med Virol. 29(2):e2029.

  35. Abd-Elhay FA, Elhusseiny KM, Kamel MG, Low SK, Sang TK, Mehyar GM, Nhat Minh LH, Hashan MR, Huy NT†. Negative Lymph Node Count and Lymph Node Ratio Are Associated With Survival in Male Breast Cancer. Clin Breast Cancer. 18(6):e1293-e1310.

  36. Elshafay A, Bendary AH, Vuong HT, Ahmed AR, Mokhtar MA, Soliman AL, Vuong NL, Bestawi IAE, Abdallah NA, Vu VT, Hirayama K, Huy NT†. Does No-Touch Technique Better than Conventional or Intermediate Saphenous Vein Harvest Techniques for Coronary Artery Bypass Graft Surgery: a Systematic Review and Meta-analysis. J Cardiovasc Transl Res. 11(6):483-494

  37. Ahmed AM, Moahammed AT, Mattar OM, Mohamed EM, Faraag EA, AlSafadi AM, Hirayama K, Huy NT†. Surgical treatment of diverticulitis and its complications: A systematic review and meta-analysis of randomized control trials. Surgeon. 16(6):372-383.

  38. Al-Habbaa A, Rawla P, Morra ME, Abotaha AA, Sakr EE, Abdo Shehata MA, Shahin KM, Abdel Mageed S, Huy NT. Valvular involvement in granulomatosis with polyangitis: Case report and systematic review of literature. Echocardiography. 35(9):1456-1463.

  39. Waqas A, Elhady M, Dila KAS, Kaboub F, Trinh LV, Nhien CH, Al-Husseini MJ, Kamel MG, Elshafay A, Nhi HY, Hirayama K, Huy NT†. Association between maternal depression and risk of infant diarrhea: a systematic review and meta-analysis. Public Health. 159:78-88

  40. Ahmed AM, Doheim MF, Mattar OM, Sherif NA, Truong DH, Hoa PTL, Hirayama K, Huy NT†. Beclabuvir in combination with asunaprevir and daclatasvir for hepatitis C virus genotype 1 infection: a systematic review and meta-analysis. Journal of Medical Virology. 90(5):907-918.

  41. Elshafay A, Truong DH, AboElnas MM, Idrees H, Metwali HG, Vuong NL, Saad OA, Hirayama K, Huy NT†. The Effect of Endothelin Receptor Antagonists in Patients with Eisenmenger Syndrome: A Systematic Review. Am J Cardiovasc Drugs. doi: 10.1007/s40256-017-0240-5.

  42. Ebied A, Vuong H, Makram O, Sang TK, Ghorab M, Ngo H, Iraqi A, Kamel MG, Dang TN, Vuong NL, Hirayama K, Huy NT†. The role of primary lymph node sites in survival and mortality prediction in Hodgkin Lymphoma: A SEER population-based retrospective study. Cancer Medicine 7(4):953-965

  43. Vuong NL, Elshafay A, Thao LP, Abdalla AR, Mohyeldin IA, Elsabaa K, Omran ES, Yu F, Hirayama K, Huy NT†. Efficacy of treatments in primary spontaneous pneumothorax: A systematic review and network meta-analysis of randomized clinical trials. Respir Med. 137:152-166.

  44. Tam DNH, Truong DH, Nguyen TTH, Quynh LN, Tran L, Nguyen HD, Shamandy BE, Le TMH, Tran DK, Sayed D, Vu VV, Mizukami S, Hirayama K, Huy NT†. Ginsenoside Rh1: A Systematic Review of Its Pharmacological Properties. Plant Medica. 84(3):139-152

  45. Kamel MG, El-Qushayri AE, Thach TQ, Huy NT†. Cardiovascular mortality trends in non-Hodgkin's lymphoma: a population-based cohort study. Expert Rev Anticancer Ther. 18(1):91-100

  46. Hallab A, Naveed S, Altibi A, Abdelkhalek M, Ngo HT, Le TP, Hirayama K, Huy NT†. Association of psychosis with antiphospholipid antibody syndrome: A systematic review of clinical studies. Gen Hosp Psychiatry. 50:137-147

  47. Mohammed AT, Khattab M, Ahmed AM, Turk T, Sakr N, Khalil A, Abdelhalim M, Sawaf B, Hirayama K, Huy NT†. The Therapeutic Effect of Probiotics on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized Control Trials. Clinical Rheumatology. 36(12):2697-2707.

  48. Elshafay A, Tinh NX, Salman S, Shaheen YS, Othman EB, Elhady MT, Kansakar AR, Tran L, Van L, Hirayama K, Huy NT†.Ginsenoside Rk1 bioactivity: a systematic review. PeerJ. 5:e3993.

  49. Nguyen AV, Thanh LV, Kamel MG, Abdelrahman SAM, El-Mekawy M, Mokhtar MA, Ali AA, Hoang NNN, Vuong NL, Abd-Elhay FA, Omer OA, Mohamed AA, Hirayama K, Huy NT†. Optimal percutaneous coronary intervention in patients with ST-elevation myocardial infarction and multivessel disease: An updated, large-scale systematic review and meta-analysis. Int J Cardiol. 244:67-76

  50. Elmaraezy A, Ebraheem Morra M, Tarek Mohammed A, Al-Habaa A, Elgebaly A, Abdelmotaleb Ghazy A, Khalil AM, Tien Huy N, Hirayama K. Risk of cataract among interventional cardiologists and catheterization lab staff: A systematic review and meta-analysis. Catheter Cardiovasc Interv. 90(1):1-9

  51. Kamel MG, Nam NT, Han NHB, El-Shabouny AE, Makram AM, Abd-Elhay FA, Dang TN, Hieu NLT, Huong VTQ, Tung TH, Hirayama K, Huy NT†. Post-dengue acute disseminated encephalomyelitis: A case report and meta-analysis. PLoS Negl Trop Dis. 11(6):e0005715

  52. Mbanefo EC, Ahmed AM, Titouna1 A, Elmaraezy A, Trang NTH, Long NP, Anh NH, Nghi TD, Hung BT, Hieu MV, Anh NK, Huy NT*, Hirayama K*. Association of glucose-6-phosphate dehydrogenase deficiency and malaria: a systematic review and meta-analysis. Scientific Reports. 7:45963

  53. Vuong HG, Altibi AM, Abdelhamid AH, Ngoc PU, Quan VD, Tantawi MY, Elfil M, Vu TL, Elgebaly A, Oishi N, Nakazawa T, Hirayama K, Katoh R, Huy NT*, Kondo T*. The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review. Oncotarget. 8(6):10637-10649.

  54. Elmaraezy A, Abushouk AI, Saad S, Eltoomy M, Mahmoud O, Hassan HM, Aboelmakarem A, Aboel Fotoh A, Althaher F, Huy NT†, Hirayama K. Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of RCTs. CNS Neurol Disord Drug Targets. 16(7):789-799

  55. Morra ME, Elgebaly A, Elmaraezy A, Khalil AM, Altibi AM, Vu TL, Mostafa MR, Huy NT†, Hirayama K. Therapeutic efficacy and safety of Botulinum Toxin A Therapy in Trigeminal Neuralgia: a systematic review and meta-analysis of randomized controlled trials. J Headache Pain. 17(1):63.

  56. Trang NT, Long NP, Hue TT, Hung le P, Trung TD, Dinh DN, Luan NT, Huy NT*, Hirayama K*. Association between nutritional status and dengue infection: a systematic review and meta-analysis. BMC Infect Dis. 16(1):172

  57. Hung BT, Long NP, Hung LP, Luan NT, Anh NH, Nghi TD, Hieu MV, Trang NTH, Rafidinarivo HF, Anh NK, Hawkes D, Huy NT*, Hirayama K*. Research trends in evidence-based medicine: a joinpoint regression analysis of more than 50 years of publication data. PLoS One 10(4):e0121054

  58. Long NP, Huy NT*, Trang NTH, Luan NT, Anh NH, Nghi TD, Hieu MV, Hirayama K, Karbwang J*. Scientific productivity on research in ethical issues over the past half century: A JoinPoint regression analysis. Tropical Medicine and Health. 42(3):121-6.

  59. Mbanefo EC, Huy NT, Wadagni AA, Eneanya CI, Nwaorgu O, Hirayama K. Host Determinants of Reinfection with Schistosomes in Humans: a Systematic Review and Meta-analysis. PLoS Negl Trop Dis. 8(9):e3164

  60. Huy NT, Hamada M, Kikuchi M, Lan NTP, Yasunami M, Zamora J, and Hirayama K. Association of HLA and post-schistosomal hepatic disorder: A systematic review and meta-analysis. Parasitol Int. 60(4):347-356.